The Definition And Examples Of Epigenetics

By Jason Wagner


This means being at the top of genetics. The turning on or off of certain genetics is known as epigenetics. This does not affect the DNA sequence, but it affects how it will be read. It can also be said to be the external modification of DNA and turns cells either on or off. It may live for the period a cell is still active, or it can last from childhood to adulthood. It can also be passed to the next generations at times.

When DNA methylation is added to a methyl group or a chemical cap, it may cause some alteration to the genetic material. It alters the physical structure of the DNA but never the sequence. This can actually lead to the suppression of some genes. This means that those genes will not have the chance to be expressed. The structure will be the same, but the physical appearance will be different.

DNA is very long. It would not be able to fit into a cell was It not for a protein known as histone. DNA does not squash the protein, however. It lays out itself comfortably. If the DNA is too tight, it will be impossible to read because of the DNA reading cells. The modifications make the histone relax, and the material is easier to read.

One may wonder, how come all the different body cells contain the same DNA but the cells are completely different. This is because the genes in every part of the body like the skin, the brain and others the genes are expressed differently. This is why the cells in all the body parts are always going to appear different.

As earlier mentioned, epigenetics can be passed from one generation to the next for a long time. This is likely to happen when they are present in the sperm cell, the egg cell or in both. However, it may not happen because of the reprogramming process. This occurs when the sperm and the egg cell combine to form a whole new cell. All the epigenetics may be erased. The fetus can start afresh.

The reprogramming is not guaranteed to happen in all the cases. This means that the epigenetics may be transferred on to the fetus. The food that was ingested before conception may actually affect the future of the baby. It is therefore important to eat well. This theory is however yet to be proved to have worked in human beings.

Epigenetics may actually have a role in the development of some cancers. Some of the genes kill the ability to control how big a cell grows. This means that the cell could overgrow at a very rapid rate. It may eventually stat to inhibit normal bodily functions in various body parts. It the end, it turns out to be a tumor.

There are cells whose job is to reconstruct damaged DNA. Some epigenetics may cause this to be impossible. This means that DNA will be damaged continually with no way of getting repaired. This is one of the ways of letting cancer out.




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